“Simulating microgravity on Earth to advance astronaut health and therapeutic innovation”
Dr. Arvind Bagde is a pharmaceutical scientist and innovator with expertise in drug delivery systems, exosome biology, simulated microgravity research, nanotechnology, transdermal formulations, and mammalian cell culture platforms. His research focuses on understanding how Earth-based simulated microgravity systems influence exosome production, cellular signaling, and biological responses relevant to space biology and translational medicine. His work involves the use of rotating wall vessel bioreactors, random positioning machines, controlled hypoxia, and bioelectrical stimulation to develop advanced mammalian cell culture models under altered-gravity conditions. Dr. Bagde is also interested in the future application of exosomes as biologically derived nanocarriers for RNA therapeutics and regenerative medicine. His long-term goal is to develop innovative bioengineering platforms that support astronaut health research, space biomanufacturing, and biomedical advancements benefiting human health on Earth.