PREPARE Challenge: Advance Early Prediction for Alzheimer's and Related Dementia

Problem Statement

Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) impact over 6 million Americans, causing progressive cognitive, functional, and behavioral impairments. Early detection is crucial, especially with emerging treatment options, but current clinical tools are not sensitive enough for early prediction. 

The National Institute on Aging (NIA), part of the National Institutes of Health (NIH), is running the PREPARE Challenge (Pioneering Research for Early Prediction of Alzheimer's and Related Dementias EUREKA Challenge) to advance solutions for accurate, innovative, and representative early prediction of AD/ADRD. To achieve this goal, the challenge will feature three phases that successively build on each other.

Anticipated Dates: 

• Phase I
  • Challenge launch - September 1, 2023
  • Executive summary drafts due - January 17, 2024
  • Submissions due - January 31, 2024
  • Finalists notified - March 18, 2024
  • Finalists provide data access for verification - June 1, 2024
  • Winners selected and notified after verification - June 17, 2024 through August 30, 2024
  • Winners publicly announced - September 2024
• Phase II
  • Challenge launch - October 22, 2024
  • Model Submissions due - December 19, 2024
  • Report Submissions due - January 22, 2025
  • Verified winners notified - March 31, 2025
  • Winners publicly announced - April 16, 2025
• Tentative Phase III Dates
  • Submissions due - July 1, 2025
  • Winners publicly announced - November 2025

Interested in competing?  Click Learn More for more information and to register!